LSD VIAL FUNDAMENTALS EXPLAINED

From the LSD-sure crystal construction, the side chain of the lid residue L209EL2 varieties in depth hydrophobic contacts with each LSD and bordering residues in TMs III, IV, and V (Determine 4C). Once the lid moved aside to reveal the binding pocket in simulation, a number of of such contacts broke. We So hypothesized that L209EL2 functions as bei